Biocompatibility of Ceramic Materials in Ca2P2O7–Ca(PO3)2 System Obtained via Heat Treatment of Cement-Salt Stone

Biocompatibility of ceramic materials in Ca2P2O7-Ca(PO3)2 system was investigated using different methods, including vitro and vivo tests. Ceramic the were obtained by annealing cement-salt stone based on powder mixtures calcium citrate tet-rahydrate Ca3(C6H5O7)2·4H2O monocalcium phosphate monohydrate (MCPM) Ca(H2PO4)2·H2O. The phase composition included brushite, monetite as a result chemical reaction starting components after adding water. presence citric acid by-product reaction, leads to increase setting time stone. Highly concentrated aqueous suspensions MCPM powders providing content polyphosphate Ca(PO3)2 up 20 wt % ceramics used for designing bioresorbable materials. an excess makes it possible reduce temperature ceramics, which is associated with formation lower melting Ca(PO3)2. In tests shown that can be recommended regenerative treatments bone defects.